Bupropion Cost in 2025: Prices for XL, 150 mg, and No-Insurance Options

Bupropion Cost Overview

If you search bupropion cost or cost of bupropion on a coupon site today, the spread is dramatic. Generic tablets can start at $2–$7 for a 30-day supply, while brand-name Wellbutrin versions still command $350 + per month in some pharmacies. The main price drivers are:

  • Formulation – immediate-release (IR) is cheapest; sustained-release (SR) and extended-release (XL) cost more to manufacture.
  • Brand vs. generic – patents expired long ago, so dozens of FDA-approved generics compete on price; brand stock is scarce and pricey.
  • Pharmacy contracts & coupons – the identical National Drug Code (NDC) may ring up at $140 in one chain and $6 next door once a digital card is scanned.

Nationwide June 2025 data show the average retail tag for generic SR 150 mg (60 tabs) at about $100, yet the lowest coupon price is $6.13 evidence that comparison shopping can slice 90 % off the cash bill.

Bupropion XL Cost

Type bupropion xl cost into GoodRx and you’ll see lows around $6.75 for 30 tablets of 150 mg XL when a coupon is applied. Without any discount, most pharmacies list generic XL at $120–$150 for the same bottle, while brand-name Wellbutrin XL 300 mg can soar to $2,700 + per month. SingleCare’s card often undercuts even those coupons, dropping a 30-count 150 mg XL refill to $6.01 in participating pharmacies.

Product (30 tabs) Typical Retail Low Coupon Notes
Generic XL 150 mg $128–$150 $6.75 GoodRx floor
Generic XL 300 mg $180 + $10–$11 Price rises with strength
Brand Wellbutrin XL 300 mg $2,724 N/A (brand rarely discounted) High because of limited stock

Smart saving moves:

  • Confirm “generic bupropion XL, substitution allowed” on the e-Rx.
  • Compare at least three local or mail-order pharmacies before checkout.
  • Opt for a 90-day fill once the dose is stable per-tablet cost usually drops 30–40 %.

Bupropion 150 mg Cost Without Insurance

Plug bupropion 150 mg cost without insurance into SingleCare’s tool and two numbers pop up: a $100.06 average cash price for 60 sustained-release tablets and a $6.13 discounted price with its free coupon same bottle, different barcode. Brand Wellbutrin SR costs roughly $558 for 60 tablets at the register, a 90-percent premium over generic.

Product & Quantity Cash Price (no coupon) With Coupon Savings
Generic SR 150 mg × 60 $100.06 $6.13 94 %
Generic XL 150 mg × 30 $128 $6.75 95 %
Brand Wellbutrin SR 150 mg × 60 $558 Coupon rarely available

Quick tips to minimize out-of-pocket spend

  • Always specify “generic bupropion 150 mg SR” on the script.
  • Screenshot your coupon barcode before heading to the counter.
  • Compare warehouse clubs, big-box stores, and independent pharmacies price swings of $100+ are common within a single ZIP code.

Curious how the same molecule doubles as an ADHD-friendly libido booster? Check out this deep-dive hub on bupropion’s

Peer reviewers

  • Albert Yeung, MDHarvard University, Cambridge MA, USA
  • Ali Madeeh Hashmi, MDDepartment of Psychiatry & Behavioral Sciences, Mayo Hospital, Lahore, Pakistan

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