Bupropion Cost in 2025: Prices for XL, 150 mg, and No-Insurance Options

Bupropion Cost Overview

If you search bupropion cost or cost of bupropion on a coupon site today, the spread is dramatic. Generic tablets can start at $2–$7 for a 30-day supply, while brand-name Wellbutrin versions still command $350 + per month in some pharmacies. The main price drivers are:

  • Formulation – immediate-release (IR) is cheapest; sustained-release (SR) and extended-release (XL) cost more to manufacture.
  • Brand vs. generic – patents expired long ago, so dozens of FDA-approved generics compete on price; brand stock is scarce and pricey.
  • Pharmacy contracts & coupons – the identical National Drug Code (NDC) may ring up at $140 in one chain and $6 next door once a digital card is scanned.

Nationwide June 2025 data show the average retail tag for generic SR 150 mg (60 tabs) at about $100, yet the lowest coupon price is $6.13 evidence that comparison shopping can slice 90 % off the cash bill.

When someone is already searching for where to buy bupropion, it is worth taking the time to read about how this medication is metabolized, how CYP2B6 variants and hydroxybupropion levels can personalize treatment, and what considerations apply when taking it during pregnancy.

Bupropion XL Cost

Type bupropion xl cost into GoodRx and you’ll see lows around $6.75 for 30 tablets of 150 mg XL when a coupon is applied. Without any discount, most pharmacies list generic XL at $120–$150 for the same bottle, while brand-name Wellbutrin XL 300 mg can soar to $2,700 + per month. SingleCare’s card often undercuts even those coupons, dropping a 30-count 150 mg XL refill to $6.01 in participating pharmacies.

Product (30 tabs) Typical Retail Low Coupon Notes
Generic XL 150 mg $128–$150 $6.75 GoodRx floor
Generic XL 300 mg $180 + $10–$11 Price rises with strength
Brand Wellbutrin XL 300 mg $2,724 N/A (brand rarely discounted) High because of limited stock

Smart saving moves:

  • Confirm “generic bupropion XL, substitution allowed” on the e-Rx.
  • Compare at least three local or mail-order pharmacies before checkout.
  • Opt for a 90-day fill once the dose is stable per-tablet cost usually drops 30–40 %.

Bupropion 150 mg Cost Without Insurance

Plug bupropion 150 mg cost without insurance into SingleCare’s tool and two numbers pop up: a $100.06 average cash price for 60 sustained-release tablets and a $6.13 discounted price with its free coupon same bottle, different barcode. Brand Wellbutrin SR costs roughly $558 for 60 tablets at the register, a 90-percent premium over generic.

Product & Quantity Cash Price (no coupon) With Coupon Savings
Generic SR 150 mg × 60 $100.06 $6.13 94 %
Generic XL 150 mg × 30 $128 $6.75 95 %
Brand Wellbutrin SR 150 mg × 60 $558 Coupon rarely available

Quick tips to minimize out-of-pocket spend

  • Always specify “generic bupropion 150 mg SR” on the script.
  • Screenshot your coupon barcode before heading to the counter.
  • Compare warehouse clubs, big-box stores, and independent pharmacies price swings of $100+ are common within a single ZIP code.

Curious how the same molecule doubles as an ADHD-friendly libido booster? Check out this deep-dive hub on bupropion’s

Peer reviewers

  • Albert Yeung, MDHarvard University, Cambridge MA, USA
  • Ali Madeeh Hashmi, MDDepartment of Psychiatry & Behavioral Sciences, Mayo Hospital, Lahore, Pakistan

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